In JavaScript, the natural primitive for "a sequence of things that arrive over time" is already in the language: the async iterable. You consume it with for await...of. You stop consuming by stopping iteration.
What TransformStreams are supposed to do is check for backpressure on the controller and use promises to communicate that back to the writer:
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In rare cases chicken pox can cause a swelling of the brain, called encephalitis; an inflammation of the lungs, called pneumonitis; and stroke, which can result in hospitalisation and - very rarely - death.